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    姚永刚课题组发现褪黑素通过抑制NLRP3炎症小体激活拮抗吗啡镇痛耐受
    近期,国际知名期刊Redox Biology发表了中科院昆明动物研究所题为Melatonin alleviates morphine analgesic tolerance in mice by decreasing NLRP3 inflammasome activation的研究论文。该研究发现褪黑素可抑制吗啡诱导的NLRP3炎症小体激活,进而拮抗吗啡镇痛耐受,阐明了褪黑素-吗啡联合使用能提高吗啡镇痛效果,减轻长期吗啡使用引起镇痛耐受的分子...
     
    第一党支部召开党员大会暨“不忘初心,弘扬优良家... (07-01)
    昆明动物所科研攻关临时党支部和李明华分别荣获中... (07-01)
    Zoological Research期刊2019影响因子升至2.638 (06-30)
    昆明动物所开展消费扶贫定向采购活动 (06-30)
    昆明动物所举行2020年瑞沃德基础医学明德奖学金颁... (06-29)
     
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    姚永刚课题组发现褪黑素通过抑制NLRP3炎症小体激活... (07-01)
    蒋学龙课题组在东喜马拉雅兽类多样性格局解析方面... (06-28)
    昆明动物所在家养动物起源与驯化方面取得重要进展 (06-25)
    东南亚野生动物多样性研究组厘定云南鮡科鱼类一新... (06-24)
    人类菌群医学生态学理论框架初见雏形 (06-12)
     
    中新社——澳洲野犬源自何处?中科院两研究“殊途... (05-28)
    中新社——中国科研人员在缅甸发现3种两栖类新纪录 (05-28)
    中新社——科研人员在抑郁症功能基因组学领域取得... (05-28)
    中新社——古DNA研究揭示悬棺葬源流历史:或起源中... (05-28)
    中国青年报——昆明动物所抑郁症功能基因组学研究... (05-28)
     
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    Shen C, Liu M, Xu R, Wang G, Li J, Chen P, Ma W, Mwangi J, Lu Q, Duan Z, Zhang Z, Dahmani FZ, Mackeigan D, Ni H, Lai R .  2020   14-3-3ζ-c-Src-integrin-β3 Complex Is Vital for Platelet Activation Blood .  doi: 10.1182/blood.2019002314
    Zhan Y, Wei J, Liang J, Xu X, He R, Robbins TW, Wang Z .  2020   Diagnostic Classification for Human Autism and Obsessive-Compulsive Disorder Based on Machine Learning From a Primate Genetic Model American Journal of Psychiatry .  doi: 10.1176/appi.ajp.2020.19101091
    Liu Q, Wei J, Li Y, Wang M, Su J, Lu Y, López MG, Qian X, Zhu Z, Wang H, Gan M, Jiang Q, Fu YX, Takiff HE, Comas I, Li F, Lu X, Fortune SM, Gao Q .  2020   Mycobacterium Tuberculosis Clinical Isolates Carry Mutational Signatures of Host Immune Environments Science Advances .  doi: 10.1126/sciadv.aba4901
    Hughes AC, Lechner AM, Chitov A, Horstmann A, Hinsley A, Tritto A, Chariton A, Li BV, Ganapin D, Simonov E, Morton K, Toktomushev K, Foggin M, Tan-Mullins M, Orr MC, Griffiths R, Nash R, Perkin S, Glémet R, Kim M, Yu DW .  2020   Horizon Scan of the Belt and Road Initiative Trends in Ecology & Evolution .  doi: 10.1016/j.tree.2020.02.005
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    Xiangdong Zheng, Ziao Fu, Deyuan Su, Yuebin Zhang, Minghui Li, Yaping Pan, Huan Li, Shufang Li, Robert A. Grassucci, Zhenning Ren, Zhengshan Hu, Xueming Li, Ming Zhou, Guohui Li, Joachim Frank & Jian Yang .  2020   Mechanism of Ligand Activation of a Eukaryotic Cyclic Nucleotide-Gated Channel Nature Structural & Molecular Biology .  doi: 10.1038/s41594-020-0433-5
    Zou P, Lee WH, Gao Z, Qin D, Wang Y, Liu J, Sun T, Gao Y .  2020   Wound Dressing From Polyvinyl Alcohol/Chitosan Electrospun Fiber Membrane Loaded With OH-CATH30 Nanoparticles Carbohydrate Polymers .  doi: 10.1016/j.carbpol.2019.115786
    Khan S, He Y, Zhang X, Yuan Y, Pu S, Kong Q, Zheng G, Zhou D .  2020   PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics Oncogene .  doi: 10.1038/s41388-020-1336-y
    An K, Zhao H, Miao Y, Xu Q, Li YF, Ma YQ, Shi YM, Shen JW, Meng JJ, Yao YG, Zhang Z, Chen JT, Bao J, Zhang M, Xue T .  2020   A Circadian Rhythm-Gated Subcortical Pathway for Nighttime-Light-Induced Depressive-Like Behaviors in Mice Nature Neuroscience .  doi: 10.1038/s41593-020-0640-8
    Jing Luo, Jing Chai, Yanling Wen, MinTao,Guoliang Lin, Xiaochuan Liu, Li Ren,Zeyu Chen, Shigang Wu , Shengnan Li, Yude Wang, Qinbo Qin, Shi Wang , Yun Gao,Feng Huang, Lu Wang, Cheng Ai, Xiaobo Wang, Lianwei L, Chengxi Ye, Huimin Yang,Mi Luo , Jie Chen, Hong Hu, Liujiao Yuan, Li Zhong, Jing Wang, Jian Xu, Zhenglin Du,Zhanshan (Sam) Ma , Robert W. Murphy, Axel Meyer, Jianfang Gui, Peng Xu,Jue Ruan, Z. Jeffrey Chen, Shaojun Liu, Xuemei Lu, Ya-ping Zhang .  2020   From Asymmetrical to Balanced Genomic Diversification during Rediploidization: Subgenomic Evolution in Allotetraploid Fish Science Advances .  DOI: 10.1126/sciadv.aaz7677
    Tang X, Fang M, Cheng R, Zhang Z, Wang Y, Shen C, Han Y, Lu Q, Du Y, Liu Y, Sun Z, Zhu L, Mwangi J, Xue M, Long C, Lai R .  2020   Iron-Deficiency and Estrogen Are Associated With Ischemic Stroke by Up-Regulating Transferrin to Induce Hypercoagulability Circulation Research .  doi: 10.1161/CIRCRESAHA.119.316453
    Kapheim KM, Jones BM, Pan H, Li C, Harpur BA, Kent CF, Zayed A, Ioannidis P, Waterhouse RM, Kingwell C, Stolle E, Avalos A, Zhang G, McMillan WO, Wcislo WT .  2020   Developmental Plasticity Shapes Social Traits and Selection in a Facultatively Eusocial Bee Proceedings of the National Academy of Sciences of the United States of America .  doi: 10.1073/pnas.2000344117
    Shao Y, Wang XB, Zhang JJ, Li ML, Wu SS, Ma XY, Wang X, Zhao HF, Li Y, Zhu HH, Irwin DM, Wang DP, Zhang GJ, Ruan J, Wu DD .  2020   Genome and Single-Cell RNA-sequencing of the Earthworm Eisenia Andrei Identifies Cellular Mechanisms Underlying Regeneration Nature Communications .  doi: 10.1038/s41467-020-16454-8
    O'Brien PA, Tan S, Yang C, Frade PR, Andreakis N, Smith HA, Miller DJ, Webster NS, Zhang G, Bourne DG .  2020   Diverse Coral Reef Invertebrates Exhibit Patterns of Phylosymbiosis ISME Journal .  doi: 10.1038/s41396-020-0671-x
    Xiong Q, Liu B, Ding M, Zhou J, Yang C, Chen Y .  2020   Hypoxia and Cancer Related Pathology Cancer Letters .  doi: 10.1016/j.canlet.2020.05.002
    Wu J, Wu Y, Rao D, Zhou T, Gong S .  2020   China's Wild Turtles at Risk of Extinction Science .  doi: 10.1126/science.abc0997
    Zhang C, Xiao X, Li T, Li M .  2020   Translational Genomics and Beyond in Bipolar Disorder Molecular Psychiatry .  doi: 10.1038/s41380-020-0782-9
    Liu T, Yang L, Han X, Ding X, Li J, Yang J .  2020   Local Sympathetic Innervations Modulate the Lung Innate Immune Responses Science Advances .  doi: 10.1126/sciadv.aay1497
    Chen H, Zeng Y, Yang Y, Huang L, Tang B, Zhang H, Hao F, Liu W, Li Y, Liu Y, Zhang X, Zhang R, Zhang Y, Li Y, Wang K, He H, Wang Z, Fan G, Yang H, Bao A, Shang Z, Chen J, Wang W, Qiu Q .  2020   Allele-aware Chromosome-Level Genome Assembly and Efficient Transgene-Free Genome Editing for the Autotetraploid Cultivated Alfalfa Nature Communications .  doi: 10.1038/s41467-020-16338-x
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