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    毛炳宇研究员团队牵头构建文昌鱼胚胎单细胞水平的细胞分化谱系
    一个受精卵是如何从单细胞发育、分化为大量不同类型的细胞、组织和器官,最终构成一个完整的生命体的,这一直是发育生物学的基本问题和长期以来的研究目标。得益于近年来单细胞测序技术和和计算生物学的发展,以“ DNA条形码”为代表的谱系示踪技术取得了长足发展。例如,发育生物学的研究人员利用该技术明确了包括小鼠、斑马鱼、非洲爪蛙以及海鞘等多...
     
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    毛炳宇研究员团队牵头构建文昌鱼胚胎单细胞水平的... (06-24)
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    Li, Qiye; Wang, Mingyue; Zhang, Pei; Liu, Yang; Guo, Qunfei; Zhu, Yuanzhen; Wen, Tinggang; Dai, Xueqin; Zhang, Xiafang; Nagel, Manuel; Dethlefsen, Bjarke Hamberg; Xie, Nianxia; Zhao, Jie; Jiang, Wei; Han, Lei; Wu, Liang; Zhong, Wenjiang; Wang, Zhifeng; Wei, Xiaoyu; Dai, Wei; Liu, Longqi; Xu, Xun; Lu, Haorong; Yang, Huanming; Wang, Jian; Boomsma, Jacobus J; Liu, Chuanyu; Zhang, Guojie; Liu, Weiwei .  2022   A Single-cell Transcriptomic Atlas Tracking the Neural Basis of Division of Labour in an Ant Superorganism Nature Ecology & Evolution .  doi: 10.1038/s41559-022-01784-1
    Dong, Feng; Zhang, Qiang; Chen, Yi-Lin; Lei, Fu-Min; Li, Shou-Hsien; Wu, Fei; Yang, Xiao-Jun .  2022   Potential Millennial-scale Avian Declines by Humans in Southern China Global Change Biology .  doi: 10.1111/gcb.16289
    Wang, Gan; Zhang, Min; Meng, Ping; Long, Chengbo; Luo, Xiaodong; Yang, Xingwei; Wang, Yunfei; Zhang, Zhiye; Mwangi, James; Kamau, Peter Muiruri; Dai, Zhi; Ke, Zunfu; Zhang, Yi; Chen, Wenlin; Zhao, Xudong; Ge, Fei; Lv, Qiumin; Rong, Mingqiang; Li, Dongsheng; Jin, Yang; Sheng, Xia; Lai, Ren .  2022   Anticarin- β Shows a Promising Anti-osteosarcoma Effect by Specifically Inhibiting CCT4 to Impair Proteostasis Acta Pharmaceutica Sinica. B .  doi: 10.1016/j.apsb.2021.12.024.
    Chen, R ; Yang, ZH ; Liu, JW; Cai, X; Huo, YX; Zhang, ZJ; Li, M; Chang, H; Luo, XJ .  2022   Functional Genomic Analysis Delineates Regulatory Mechanisms of GWAS-identified Bipolar Disorder Risk Variants Genome Medicine .  doi: 10.1186/s13073-022-01057-3
    Ren, YD; Zhang, Q; Yan, XH ; Hou, DM ; Huang, HW; Li, CH; Rao, DQ; Li, YX .  2022   Genomic Insights into the Evolution of the Critically Endangered Soft-shelled Turtle Rafetus Swinhoei Molecular Ecology Resources .  doi: 10.1111/1755-0998.13596.
    Yuwei Li, Chencheng Yang, Huishan Wang, Ling Zhao, Qinghua Kong, Yu Cang, Shuhua Zhao, Longbao Lv, Yan Li, Bingyu Mao, Pengcheng Ma .  2022   Sequential Stabilization of RNF220 by RLIM and ZC4H2 during Cerebellum Development and Shh-group Medulloblastoma Progression Journal of Molecular Cell Biology .  doi: 10.1093/jmcb/mjab082
    Shen, QS; Han, YF ; Wu, K ; He, YM ; Jiang, XL; Liu, PS; Xia, CF; Xiong, QX; Liu, R ; Chen, QM ; Zhang, Y; Zhao, S; Yang, CP ; Chen, YB .  2022   MrgprF Acts as a Tumor Suppressor in Cutaneous Melanoma by Restraining PI3K/Akt Signaling Signal Transduction and Targeted Therapy .  DOI10.1038/s41392-022-00945-9
    Xiao, FH ; Yu, Q ; Deng, ZL ; Yang, K ; Ye, YS ; Ge, MX ; Yan, DJ; Wang, HT ; Chen, XQ; Yang, LQ ; Yang, BY; Lin, R ; Zhang, W ; Yang, XL; Dong, L; He, YH; Zhou, JM ; Cai, WW ; Li, J ; Kong, QP .  2022   ETS1 Acts as a Regulator of Human Healthy Aging via Decreasing Ribosomal Activity Science Advances .  DOI10.1126/sciadv.abf2017
    Feng, SH ; Bai, M ; Rivas-Gonzalez, I ; Li, C ; Liu, SP ; Tong, YJ ; Yang, HD ; Chen, GJ ; Xie, D ; Sears, KE ; Franco, LM ; Gaitan-Espitia, JD ; Nespolo, RF ; Johnson, WE ; Yang, HM; Brandies, PA ; Hogg, CJ ; Belov, K; Renfree, MB; Helgen, KM ; Boomsma, JJ; Schierup, MH; Zhang, GJ .  2022   Incomplete Lineage Sorting and Phenotypic Evolution in Marsupials Cell .  DOI10.1016/j.cell.2022.03.034
    Zhiye Zhang, Chuanbin Shen, Mingqian Fang, Yajun Han, Chengbo Long, Weihui Liu, Min Yang, Ming Liu, Dengdeng Zhang, Qiqi Cao, Xue Chen, Yaqun Fang, Qiumin Lu, Zongliu Hou, Yaxiong Li, Zhenze Liu, Xi Lei, Heyu Ni, Ren Lai .  2022   Novel Contact-kinin Inhibitor Sylvestin Targets Thromboinflammation and Ameliorates Ischemic Stroke Cellular and Molecular Life Sciences .  doi: 10.1007/s00018-022-04257-7
    Hui Wang, Haibo Xu, Wei Chen, Mei Cheng, Li Zou, Qin Yang, Chi Bun Chan, Hao Zhu, Ceshi Chen, Jian-Yun Nie, Baowei Jiao .  2022   Rab13 Sustains Breast Cancer Stem Cells by Supporting Tumor-stroma Crosstalk Cancer Research .  doi: 10.1158/0008-5472.CAN-21-4097
    Wei Gao, Chuan-Xin Yu, Wei-Wei Zhou, Bao-Lin Zhang, E Anne Chambers, Hollis A Dahn, Jie-Qiong Jin, Robert W Murphy, Ya-Ping Zhang, Jing Che .  2022   Species Persistence with Hybridization in Toad-Headed Lizards Driven by Divergent Selection and Low Recombination Molecular Biology and Evolution .  doi: 10.1093/molbev/msac064
    Li, GH; Han, FF ; Xiao, FH ; Gu, KSY; Shen, Q; Xu, WH; Li, WX; Wang, YL; Liang, B; Huang, JF; Xiao, WZ; Kong, QP .  2022   System-level Metabolic Modeling Facilitates Unveiling Metabolic Signature in Exceptional Longevity Aging Cell .  doi: 10.1111/acel.13595
    Yinqiu Ji, Christopher C M Baker, Viorel D Popescu, Jiaxin Wang, Chunying Wu, Zhengyang Wang, Yuanheng Li, Lin Wang, Chaolang Hua, Zhongxing Yang, Chunyan Yang, Charles C Y Xu, Alex Diana, Qingzhong Wen, Naomi E Pierce, Douglas W Yu .  2022   Measuring Protected-area Effectiveness Using Vertebrate Distributions from Leech iDNA Nature Communications .  doi: 10.1038/s41467-022-28778-8
    Zhen Liu, Peng Chen, Dong-Ming Xu, Fei-Yan Qi, Yuan-Ting Guo, Qi Liu, Jing Bai, Xin Zhou, Peng Shi .  2022   Molecular Convergence and Transgenic Evidence Suggest a Single Origin of Laryngeal Echolocation in Bats iScience .  doi: 10.1016/j.isci.2022.104114
    Guangshi Du, Jian Sun, Zhen Li, Qian Zhang, Wenjing Liu, Chuanyu Yang, Ping Zhao, Xinye Wang, Qiyan Yin, Yao Luo, Jinhuan Song, Yi Wen, Haixia Wang, Chuan-Huizi Chen, Guosheng Hu, Zhongmei Zhou, Xiaoyun Mao, Wen Liu, Zhenzhen Liu, Dewei Jiang, Ceshi Chen .  2022   A Feedforward Circuit between KLF5 and lncRNA KPRT4 Contributes to Basal-like Breast Cancer Cancer Letters .  doi: 10.1016/j.canlet.2022.215618
    Liu, K; Jiang, LP; Shi, YL; Liu, BY; He, YM; Shen, QS; Jiang, XL; Nie, Z; Pu, J; Yang, CP; Chen, YB .  2022   Hypoxia-induced GLT8D1 Promotes Glioma Stem Cell Maintenance by Inhibiting CD133 Degradation through N-linked Glycosylation Cell Death and Differentiation .  DOI10.1038/s41418-022-00969-2
    Liu, R; Yang, GX; Bao, M; Zhou, ZM; Mao, XY ; Liu, WJ; Jiang, XY; Zhu, D; Ren, XL; Huang, J; Chen, CS .  2022   STAMBPL1 Promotes Breast Cancer Cell Resistance to Cisplatin Partially by Stabilizing MKP-1 Expression Oncogene .  DOI10.1038/s41388-022-02252-7
    Huang, XS; Tian, RR ; Ma, MD; Luo, RH; Yang, LM ; Peng, GH; Zhang, M; Dong, XQ; Zheng, YT .  2022   Bromodomain and Extra-Terminal Inhibitor BMS-986158 Reverses Latent HIV-1 Infection In Vitro and Ex Vivo by Increasing CDK9 Phosphorylation and Recruitment Pharmaceuticals .  DOI10.3390/ph15030338
    Mingqian Fang, Xiaopeng Tang, Juan Zhang, Zhiyi Liao, Gan Wang, Ruomei Cheng, Zhiye Zhang, Hongwen Zhao, Jing Wang, Zhaoxia Tan, Peter Muiruri Kamau, Qiumin Lu, Qi Liu, Guohong Deng, Ren Lai .  2022   An Inhibitor of Leukotriene-A 4 Hydrolase from Bat Salivary Glands Facilitates Virus Infection Proceedings of the National Academy of Sciences of the United States of America .  doi10.1073/pnas.2110647119
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