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    中文移动版 英文移动版
    罗雄剑课题组在精神分裂症整合组学研究方面取得新进展
    精神分裂症( Schizophrenia , SCZ )是一种病因未明的重性精神疾病。SCZ的全球终身患病率约为1% ,常发病于青壮年,且不到50%患者能获得较好预后。虽然在过去的数十年中,精神分裂症全基因组范围内的关联研究( GWAS )鉴别到系列风险遗传变异,但由于遗传异质性和连锁不平衡,如何从GWAS发现的基因座中进一步鉴别风险基因仍然是个挑战。整合组学研究为...
     
    昆明动物所召开安全工作会议 (04-12)
    昆明动物所农业资源保存与分子育种基地-昆明基地项... (04-12)
    昆明动物所召开党史学习教育部署推进会 (04-07)
    昆明动物所召开2021年度党委理论学习中心组第一次... (04-07)
    昆明动物所研究生心理健康与职业规划教育开讲 (04-02)
     
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    昆明动物所揭示史前以来的人类干扰是绿孔雀走向濒... (04-07)
    进化基因组学与基因起源研究组在云南发现三个萤火... (04-01)
    罗雄剑课题组在精神分裂症整合组学研究方面取得新进展 (04-01)
    昆明动物所等合作发表新冠病毒基因组演化分析及谱... (03-30)
    昆明动物所与美国佛罗里达自然历史博物馆合作完成... (03-10)
     
    朝闻天下:科学家揭示人类大脑进化基因组调控机制 (02-26)
    中国新闻网:中国科研人员揭示人类大脑进化的基因... (02-26)
    中国新闻网:如何从水生到陆生?中国科学家领导揭... (02-26)
    中国科学报:至少是人类13倍!非洲肺鱼基因组破解 (02-26)
    中国科学报:新研究揭示脊椎动物“登陆”之谜 (02-26)
     
    Han Y, Luo A, Kamau PM, Takomthong P, Hu J, Boonyarat C, Luo L, Lai R .  2021   A Plant-derived TRPV3 Inhibitor Suppresses Pain and Itch British Journal of Pharmacology .  doi: 10.1111/bph.15390
    Jiang J, Cheng L, Yan L, Ge M, Yang L, Ying H, Kong Q .  2021   Decoding the Role of Long Noncoding RNAs in the Healthy Aging of Centenarians Briefings in Bioinformatics .  doi: 10.1093/bib/bbaa439
    Zheng HY, Xu M, Yang CX, Tian RR, Zhang M, Li JJ, Wang XC, Ding ZL, Li GM, Li XL, He YQ, Dong XQ, Yao YG, Zheng YT .  2021   Longitudinal Transcriptome Analyses Show Robust T cell Immunity during Recovery from COVID-19 Signal Transduction and Targeted Therapy .  doi: 10.1038/s41392-020-00457-4
    Huang, Maobo; Zhou, Yuanfei; Duan, Dongzhu; Yang, Chuanyu; Zhou, Zhongmei; Li, Fubing; Kong, Yanjie; Hsieh, Yi-Ching; Zhang, Ruihan; Ding, Wenping; Xiao, Weilie; Puno, PemaTenzin; Chen, Ceshi .  2021   Targeting Ubiquitin Conjugating Enzyme UbcH5b by a Triterpenoid PC3-15 from Schisandra Plants Sensitizes Triple-negative Breast Cancer Cells to Lapatinib Cancer Letters .  10.1016/j.canlet.2021.02.009
    Qiao, Jingxin; Li, Yue-Shan; Zeng, Rui; Liu, Feng-Liang; Luo, Rong-Hua; Huang, Chong; Wang, Yi-Fei; Zhang, Jie; Quan, Baoxue; Shen, Chenjian; Mao, Xin; Liu, Xinlei; Sun, Weining; Yang, Wei; Ni, Xincheng; Wang, Kai; Xu, Ling; Duan, Zi-Lei; Zou, Qing-Cui; Zhang, Hai-Lin; Qu, Wang; Long, Yang-Hao-Peng; Li, Ming-Hua; Yang, Rui-Cheng; Liu, Xiaolong; You, Jing; Zhou, Yangli; Yao, Rui; Li, Wen-Pei; Liu, Jing-Ming; Chen, Pei; Liu, Yang; Lin, Gui-Feng; Yang, Xin; Zou, Jun; Li, Linli; Hu, Yiguo; Lu, Guang-Wen; Li, Wei-Min; Wei, Yu-Quan; Zheng, Yong-Tang; Lei, Jian; Yang, Shengyong .  2021   SARS-CoV-2 M pro Inhibitors with Antiviral Activity in a Transgenic Mouse Model Science .  10.1126/science.abf1611
    Zhong, Benfu; Jiang, Dewei; Hong, Yang; Li, Lifang; Qiu, Li; Yang, Ronghui; Jin, Xiaohan; Song, Yawen; Chen, Ceshi; Li, Binghui .  2021   Glucose-6-phosphate Dehydrogenase Neutralizes Stresses by Supporting Reductive Glutamine Metabolism and AMPK Activation Signal Transduction and Targeted Therapy .  10.1038/s41392-020-00399-x
    Wang, Kun; Wang, Jun; Zhu, Chenglong; Yang, Liandong; Ren, Yandong; Ruan, Jue; Fan, Guangyi; Hu, Jiang; Xu, Wenjie; Bi, Xupeng; Zhu, Youan; Song, Yue; Chen, Huatao; Ma, Tiantian; Zhao, Ruoping; Jiang, Haifeng; Zhang, Bin; Feng, Chenguang; Yuan, Yuan; Gan, Xiaoni; Li, Yongxin; Zeng, Honghui; Liu, Qun; Zhang, Yaolei; Shao, Feng; Hao, Shijie; Zhang, He; Xu, Xun; Liu, Xin; Wang, Depeng; Zhu, Min; Zhang, Guojie; Zhao, Wenming; Qiu, Qiang; He, Shunping; Wang, Wen .  2021   African Lungfish Genome Sheds Light on the Vertebrate Water-to-land Transition Cell .  10.1016/j.cell.2021.01.047
    Bi, Xupeng; Wang, Kun; Yang, Liandong; Pan, Hailin; Jiang, Haifeng; Wei, Qiwei; Fang, Miaoquan; Yu, Hao; Zhu, Chenglong; Cai, Yiran; He, Yuming; Gan, Xiaoni; Zeng, Honghui; Yu, Daqi; Zhu, Youan; Jiang, Huifeng; Qiu, Qiang; Yang, Huanming; Zhang, Yong E; Wang, Wen; Zhu, Min; He, Shunping; Zhang, Guojie .  2021   Tracing the Genetic Footprints of Vertebrate Landing in Non-teleost Ray-finned Fishes Cell .  10.1016/j.cell.2021.01.046
    Luo, Xin; Liu, Yuting; Dang, Dachang; Hu, Ting; Hou, Yingping; Meng, Xiaoyu; Zhang, Fengyun; Li, Tingting; Wang, Can; Li, Min; Wu, Haixu; Shen, Qiushuo; Hu, Yan; Zeng, Xuerui; He, Xiechao; Yan, Lanzhen; Zhang, Shihua; Li, Cheng; Su, Bing .  2021   3D Genome of Macaque Fetal Brain Reveals Evolutionary Innovations during Primate Corticogenesis Cell .  10.1016/j.cell.2021.01.001
    Guo, Yaqiong; Luo, Ronghua; Wang, Yaqing; Deng, Pengwei; Song, Tianzhang; Zhang, Min; Wang, Peng; Zhang, Xu; Cui, Kangli; Tao, Tingting; Li, Zhongyu; Chen, Wenwen; Zheng, Yongtang; Qin, Jianhua .  2021   SARS-CoV-2 Induced Intestinal Responses with a Biomimetic Human Gut-on-chip Science Bulletin .  10.1016/j.scib.2020.11.015
    Min Zhang, Peng Wang, Ronghua Luo, Yaqing Wang, Zhongyu Li, Yaqiong Guo, Yulin Yao, Minghua Li, Tingting Tao, Wenwen Chen, Jianbao Han, Haitao Liu, Kangli Cui, Xu Zhang, Yongtang Zheng, Jianhua Qin .  2021   Biomimetic Human Disease Model of SARS-CoV-2 Induced Lung Injury and Immune Responses on Organ Chip System Advanced Science .  10.1002/advs.202002928
    Hao Li, Ling-Yan Su, Lixin Yang, Min Li, Qianjin Liu, Zhenhui Li, Yan Hu,Hongwei Li,Shihao Wu,Wenchao Wang, Yingzhou Hu, Zhengbo Wang , Joshua D.Rizak,Baihui Huang, Min Xu, Jing Wu ,Long-Bao Lv,Christoph W. Turck, Yong yin,Yong-Gang Yao, Bing Su,Xintian Hu .  2020   A Cynomolgus Monkey with Naturally Occurring Parkinson's Disease National Science Review
    Li, JZ; Shang, YF ; Wang, L ; Zhao, B ; Sun, CL ; Li, JL; Liu, SL; Li, C ; Tang, M ; Meng, FL ; Zheng, P .  2020   Genome Integrity and Neurogenesis of Postnatal Hippocampal Neural Stem/progenitor Cells Require a Unique Regulator Filia Science Advances .  doi: 10.1126/sciadv.aba0682
    Hui-Juan Li, Chen Zhang, Li Hui, Dong-Sheng Zhou, Yi Li, Chu-Yi Zhang, Chuang Wang, Lu Wang, Wenqiang Li, Yongfeng Yang, Na Qu, Jinsong Tang , Ying He, Jun Zhou, Zihao Yang , Xingxing Li, Jun Cai,Lu Yang ,Jun Chen,Weixing Fan, Wei Tang,Wenxin Tang,Qiu-Fang Jia, Weiqing Liu,Chuanjun Zhuo,Xueqin Song, Fang Liu,Yan Bai,Bao-Liang Zhong,Shu-Fang Zhang,Jing Chen,Bin Xia, Luxian Lv,Zhongchun Liu,Shaohua Hu,Xiao-Yan Li,Jie-Wei Liu,Xin Cai,Yong-Gang Yao,Yuyanan Zhang, Hao Yan,Suhua Chang,Jing-Ping Zhao,Wei-Hua Yue,Xiong-Jian Luo,Xiaogang Chen,Xiao Xiao,Yiru Fang,Ming Li .  2020   Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis JAMA Psychiatry .  10.1001/jamapsychiatry.2020.3738
    Yang, Xing-Yan; Rakha, Allah; Chen, Wei; Hou, Juzhi; Qi, Xue-Bin; Shen, Quan-Kuan; Dai, Shan-Shan; Sulaiman, Xierzhatijiang; Abdulloevich, Najmudinov Tojiddin; Afanasevna, Manilova Elena; Ibrohimovich, Khudoidodov Behruz; Chen, Xi; Yang, Wei-Kang; Adnan, Atif; Zhao, Ruo-Han; Yao, Yong-Gang; Su, Bin; Peng, Min-Sheng; Zhang, Ya-Ping .  2020   Tracing the Genetic Legacy of the Tibetan Empire in the Balti Molecular Biology and Evolution .  10.1093/molbev/msaa313
    Zhanshan Sam Ma .  2020   Predicting the Outbreak Risks and Inflection Points of COVID-19 Pandemic with Classic Ecological Theories Advanced Science .  10.1002/advs.202001530
    Wendy Li, Zhanshan Sam Ma .  2020   Dominance network analysis of the healthy human vaginal microbiome not dominated by Lactobacillus species Computational and Structural Biotechnology Journal .  10.1016/j.csbj.2020.10.033
    Ningbo Chen , Lele Ren, Linyao Du, Jiawen Hou, Victoria E Mullin, Duo Wu, Xueye Zhao, Chunmei Li, Jiahui Huang , Xuebin Qi, Marco Rosario Capodiferro, Alessandro Achilli, Chuzhao Lei, Fahu Chen, Bing Su, Guanghui Dong, Xiaoming Zhang .  2020   Ancient Genomes Reveal Tropical Bovid Species in the Tibetan Plateau Contributed to the Prevalence of Hunting Game until the Late Neolithic Proceedings of the National Academy of Sciences of the USA .  doi: 10.1073/pnas.2011696117
    Xin, JX; Zhang, H ; He, YX ; Duren, Z ; Bai, CJ ; Chen, L ; Luo, X ; Yan, DS; Zhang, CY; Zhu, X ; Yuan, QY; Feng, ZY ; Cui, CY; Qi, XB ; Ouzhuluobu ; Wong, WH ; Wang, Y; Su, B .  2020   Chromatin Accessibility Landscape and Regulatory Network of High-altitude Hypoxia Adaptation Nature Communications .  DOI: 10.1038/s41467-020-18638-8
    Adeola Oluwakemi Ayoola, Bao-Lin Zhang 1, Richard P Meisel, Lotanna M Nneji, Yong Shao, Olanrewaju B Morenikeji, Adeniyi C Adeola, Said I Ng'ang'a, Babafemi G Ogunjemite,Agboola O Okeyoyin ,Christian Roos,Dong-Dong Wu .  2020   Population Genomics Reveals Incipient Speciation, Introgression, and Adaptation in the African Mona Monkey (Cercopithecus mona) Molecular Biology and Evolution .  doi: 10.1093/molbev/msaa248
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