王国栋
王国栋.jpg
研究员,特聘青年研究员,2004年毕业于山东大学生命科学学院获学士学位,2010年于中国科学院昆明动物研究所获得动物学博士学位,随后留所工作。期间至中科院北京基因组研究所和牛津大学学术访问。
个人简介 

    近年来已在Nature GeneticsNature CommunicationsPNASCell ResearchMolecular Biology and EvolutionNucleic Acids Research等国际著名SCI期刊发表论文20余篇。

    受邀为  Nature Communications, Molecular Biology and EvolutionPLoS GeneticsBMC Genomics等国际知名期刊审稿。

   2017.01  至今      研究员,特聘青年科学家 

2015.11  2016.03   牛津大学,访问学者 

2014.01  2016.12   中国科学院昆明动物研究所,副研究员 

2010.01  2011.12   中国科学院北京基因组研究所,访问学者 

2010.07  2013.12   中国科学院昆明动物研究所,助理研究员 

2004.09  2010.06   中国科学院昆明动物研究所,获博士学位 

2000.09  2004.06   山东大学生命科学学院,获学士学位 .

承担项目

 1. 中国科学院青年创新促进会会员,2015年。 

2. 第十七批云南省中青年学术和技术带头人后备人才,2014HB0442014/10-2017/10 

3. 国家自然科学基金重大研究计划集成项目,9153130012,家犬在人工选择下的微进化研究,2016/01-2018/12336万元,主持。 

4. 国家重点基础研究发展计划(973计划),2013CB835202,家犬性状进化的遗传和基因组基础,2013/01-2017/08300万,课题负责人。 

    5. 国家自然科学基金重大研究计划培育项目,91231108,家犬在人工选择下的高原适应机制研究,2013/01-2015/1290万元,主持。

主要研究方向及内容    

主要从事群体基因组学和复杂性状进化和遗传机制研究,以家犬为主要研究对象。研究方向为:1)家犬的驯化历史和趋同进化;2)人工选择和自然选择的遗传机制;3)复杂性状产生和进化的遗传机制。

代表性论文    

#第一作者;*通讯作者) 

1. Bixia Tang, Qing Zhou, Lili Dong, Wulue Li, Xiangquan Zhang, Li Lan, Shuang Zhai, Jingfa Xiao, Zhang Zhang, Yiming Bao, Ya-Ping Zhang, Guo-Dong Wang#, Wenming Zhao: iDog: an integrated resource for domestic dogs and wild canids. Nucleic Acids Research 10/2018;, DOI:10.1093/nar/gky1041 

2. Guo-Dong Wang, Xiu-Juan Shao, Bing Bai, Junlong Wang, Xiaobo Wang, Xue Cao, Yan-Hu Liu, Xuan Wang, Ting-Ting Yin, Shao-Jie Zhang, Yan Lu, Zechong Wang, Lu Wang, Wenming Zhao, Bing Zhang, Jue Ruan, and Ya-Ping Zhang: Structure variation during dog domestication: insight from grey wolf and dhole genomes. National Science Review 7/2018 nwy076, https://doi.org/10.1093/nsr/nwy076 

3.Shyam Gopalakrishnan, Mikkel-Holger S. Sinding, Jazmín Ramos-Madrigal, Jonas Niemann, Jose A. Samaniego Castruita, Filipe G. Vieira, Christian Car?e, Marc de Manuel Montero, Lukas Kuderna, Aitor Serres, Víctor Manuel González-Basallote, Yan-Hu Liu, Guo-Dong Wang, Tomas Marques-Bonet, Siavash Mirarab, Carlos Fernandes, Philippe Gaubert, Klaus-Peter Koepfli, Jane Budd, Eli Knispel Rueness, Mads Peter Heide-J?rgensen, Bent Petersen, Thomas Sicheritz-Ponten, Lutz Bachmann, ?ystein Wiig, Anders J. Hansen, M. Thomas P. Gilbert: Interspecific Gene Flow Shaped the Evolution of the Genus Canis. Current Biology 10/2018; 28(21)., DOI:10.1016/j.cub.2018.08.041 

4.Yalan Han, Bowen Li, Ting-Ting Yin, Cheng Xu, Rose Ombati, Lei Luo, Yujie Xia, Lizhen Xu, Jie Zheng, Yaping Zhang, Fan Yang, Guo-Dong Wang#, Shilong Yang, Ren Lai: Molecular mechanism of the tree shrew’s insensitivity to spiciness. PLoS Biology 07/2018; 16(7):e2004921., DOI:10.1371/journal.pbio.2004921 

5.Guo-Dong Wang, Bao-Lin Zhang, Wei-Wei Zhou, Yong-Xin Li, Jie-Qiong Jin, Yong Shao, He-chuan Yang, Yan-Hu Liu, Fang Yan, Hong-Man Chen, Li Jin, Feng Gao, Yaoguang Zhang, Haipeng Li, Bingyu Mao, Robert W. Murphy, David B. Wake, Ya-Ping Zhang, Jing Che: Selection and environmental adaptation along a path to speciation in the Tibetan frog Nanorana parkeri. Proceedings of the National Academy of Sciences 05/2018; 115(22):201716257., DOI:10.1073/pnas.1716257115 

6.Hechuan Yang, Guodong Wang, Meng Wang, Yaping Ma, Tingting Yin, Ruoxi Fan, Hong Wu, Li Zhong, David M. Irwin, Weiwei Zhai, Yaping Zhang: The origin of chow chows in the light of the East Asian breeds. BMC Genomics 12/2017; 18(1)., DOI:10.1186/s12864-017-3525-9 

7.Yan-Hu Liu, Lu Wang, Tao Xu, Xiaomin Guo, Yang Li, Ting-Ting Yin, He-Chuan Yang, Hu Yang, Adeniyi C Adeola, Oscar J Sanke, Newton O Otecko, Meng Wang, Yaping Ma, Olaogun S Charles, Mikkel-Holger S Sinding, Shyam Gopalakrishnan, José Alfredo Samaniego, Anders J Hansen, Carlos Fernandes, Philippe Gaubert, Jane Budd, Philip M Dawuda, Eli Knispel Rueness, Lubin Jiang, Weiwei Zhai, M Thomas P Gilbert, Min-Sheng Peng, Xiaopeng Qi, Guo-Dong Wang#, Ya-Ping Zhang: Whole-Genome Sequencing of African Dogs Provides Insights into Adaptations against Tropical Parasites. Molecular Biology and Evolution 10/2017; 35(2)., DOI:10.1093/molbev/msx258 

8.Adeniyi C. Adeola, Sheila C. Ommeh, Jiao-Jiao Song, S. Charles Olaogun, Oscar J. Sanke, Ting-Ting Yin, Guo-Dong Wang, Shi-Fang Wu, Zhong-Yin Zhou, Jacqueline K. Lichoti, Bernard R. Agwanda, Philip M. Dawuda, Robert W. Murphy, Min-Sheng Peng, Ya-Ping Zhang: A cryptic mitochondrial DNA link between North European and West African dogs. Journal of Genetics and Genomics 03/2017; 44(3):163-170. 

9.Zeinab Amiri Ghanatsaman, Adeniyi C. Adeola, Masood Asadi Fozi, Ya-Ping Ma, Min-Sheng Peng, Guo-Dong Wang, Ali Esmailizadeh, Ya-Ping Zhang: Mitochondrial DNA sequence variation in Iranian native dogs. 03/2017; 29(3):1-9., DOI:10.1080/24701394.2017.1289375 

10.Newton O Otecko, Min-Sheng Peng, He-Chuan Yang, Ya-Ping Zhang, Guo-Dong Wang#: Re-evaluating data quality of dog mitochondrial, Y chromosomal, and autosomal SNPs genotyped by SNP array. Zoological Research 12/2016; 37(6):358-362., DOI:10.13918/j.issn.2095-8137.2016.6.358 

11.Lu WANG, Ya-Ping MA, Qi-Jun ZHOU, Ya-Ping ZHANG, Peter SAVOLAINEN, Guo-Dong WANG#: The geographical distribution of grey wolves (Canis lupus) in China: a systematic review. Zoological Research 11/2016; 37(6):315-326., DOI:10.13918/j.issn.2095-8137.2016.6.315 

12.Adeniyi Charles Adeola, Guo-Dong Wang, Sheila C Ommeh, Robert W Murphy, Sunday Olaogun: A cryptic mitochondrial DNA link between North European and West African dogs. Journal of Genetics and Genomics 10/2016; 44(3)., DOI:10.1016/j.jgg.2016.10.008 

13.Hong Wu, Yan-Hu Liu, Guo-Dong Wang, Chun-Tao Yang, Newton O. Otecko, Fei Liu, Shi-Fang Wu, Lu Wang, Li Yu, Ya-Ping Zhang: Identifying molecular signatures of hypoxia adaptation from sex chromosomes: A case for Tibetan Mastiff based on analyses of X chromosome. Scientific Reports 10/2016; 6:35004., DOI:10.1038/srep35004 

14.Mingqiang Rong, Jiangxin Liu, Meilin Zhang, Gan Wang, Gang Zhao, Guodong Wang, Yaping Zhang, Kaifeng Hu, Ren Lai: A sodium channel inhibitor ISTX-I with a novel structure provides a new hint at the evolutionary link between two toxin folds. Scientific Reports 07/2016; 6:29691., DOI:10.1038/srep29691 

15.Li Yu, Guo-Dong Wang*, Jue Ruan, Yong-Bin Chen, Cui-Ping Yang, Xue Cao, Hong Wu, Yan-Hu Liu, Zheng-Lin Du, Xiao-Ping Wang, Jing Yang, Shao-Chen Cheng, Li Zhong, Lu Wang, Xuan Wang, Jing-Yang Hu, Lu Fang, Bing Bai, Kai-Le Wang, Na Yuan, Shi-Fang Wu, Bao-Guo Li, Jin-Guo Zhang, Ye-Qin Yang, Cheng-Lin Zhang, Yong-Cheng Long, Hai-Shu Li, Jing-Yuan Yang, David M Irwin, Oliver A Ryder, Ying Li, Chung-I Wu, Ya-Ping Zhang: Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation. Nature Genetics 07/2016; 48(8)., DOI:10.1038/ng.3615 

 

 

 

 

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